Farmacéuticos Comunitarios. 2021 Oct 06; 13(4):5-11 DOI: 10.33620/FC.2173-9218.(2021/Vol13).004.02

The influence of tobacco dependence on blood pressure control in people on antihypertensive drug treatment

Penín Álvarez Ó1, Rojo Fernández JC2, Penín Rodríguez A3, Villasuso Cores B4
1. Farmacéutico comunitario. Farmacia Penín. Celanova (Ourense). 2. Médico de atención primaria. Centro de Salud Celanova (Ourense). 3. Licenciado en Químicas. 4. Farmacéutica comunitaria. Farmacia Mugardos. Mugardos (A Coruña).
Penín Ó, Rojo JC, Penín A, Villasuso B. Influencia de la dependencia del consumo de tabaco en el control de la presión arterial en personas con tratamiento farmacológico antihipertensivo. Farmacéuticos Comunitarios. 2021 Oct 06; 13 (4): 5-11 DOI: 10.33620/FC.2173-9218.(2021/Vol13).004.02
Abstract : 

Smoking and hypertension are significant cardiovascular risk factors with a relationship that remains unclear.

Objective: To check for differences between smokers and non-smokers in blood pressure (BP) values obtained in a clinic, during activity, and at night, as well as white-coat hypertension, masked hypertension and the circadian profile.

Patients and methods: Consecutive opportunistic sampling of people on antihypertensive drug treatment who attended two community pharmacies between January 2013 and August 2019.

All of them underwent isolated measurement and ambulatory blood pressure monitoring (ABPM) for 24 hours.

Results: The sample consisted of 91 smokers and 573 non-smokers with an average age of 55.9 and 66.1 respectively, with males comprising 64.8% and 50.6%, respectively.

The following showed significant differences in the values between smoking and non-smoking patients: activity-related blood pressure (SBP/DBP): 132/80 mmHg smokers, 129/75 mmHg non-smokers. Masked uncontrolled hypertensive patients: 13.2% smokers, 12.0% non-smokers. Non-dipper profile: 34.0% smokers, 44.2% non-smokers.

Conclusions: Smokers had the highest blood pressure during periods of activity, and their higher prevalence of masked uncontrolled hypertension and dipper profile than non-smokers was statistically significant.

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