Introduction: The e-receipt finished its implantation in the Valencian Community (CV) in September 2013, observing that the patient did not withdraw part of the medicines prescribed, so a study is designed to find out the various incidents that could be the cause. 

Objectives: To analyze and quantify the incidences detected in the dispensation of the e-recipes prescribed to patients in community pharmacy (FC) de la CV. 

Methods: Observational, cross-sectional, prospective multicenter population-based study of the incidences detected in the dispensations of the e-recipes. The target population: patients over 18 years of age, or caregivers. 

Results: 22,983 requests for medicines or health products (HP) were recorded for 6,621 patients. Of the medicines or HP available for dispensing, 12.0% were rejected.

   • Discrepancies between what the doctor prescribed and what the patient understood accounted for 19.0% of refusals.

   • The different reasons related to non-compliance were 32.3% of medicines or health products (HP).

   • In those medicines where the patient had to pay a contribution, the rejection was slightly higher (12.2%) than in the case of those who did not. 

Conclusions: The dispensing of prescribed medicines/HP through the e-prescription makes it possible to identify drug related problem DRPs that affect the lack of adherence and discrepancies with what is prescribed in the electronic prescription.