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Farm Comunitarios. 2022 Oct 21;14(4):27-33. doi: 10.33620/FC.2173-9218.(2022/Vol14).004.04
Can the use of cetylpyridinium chloride mouthwashes reduce the transmission of SARS-CoV-2?
Gómez-Mateos M. Can the use of cetylpyridinium chloride mouthwashes reduce the transmission of SARS-CoV-2?. Farm Comunitarios. 2022 Oct 21;14(4):27-33. doi: 10.33620/FC.2173-9218.(2022/Vol14).004.04
Abstract :
Confirmed COVID-19 patients have a high viral load in the oral cavity. For this reason, at the beginning of the pandemic, the scientific community focused on mouthwashes formulated with antiseptics such as cetylpyridinium chloride (CPC) to reduce the risk of transmission among the population, which even came to be recommended in the clinical and dental practice without knowing its real effectiveness. The objective of this review is to collect those in vitro studies and clinical trials that have rigorously evaluated the application of these mouthwashes for daily use to determine their inhibitory activity against SARS-CoV-2 in saliva, and to know the correlation of the studies between the experimental conditions and those that occur in the oral cavity of patients.
Keywords :
Cetylpyridinium chloride, mouthwash, covid prophylaxis, antiviral agents, SARS-CoV-2
Editor: © SEFAC. Sociedad Española de Farmacia Clínica, Familiar y Comunitaria.
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